Lit Review Magic: The Evidence for Psychedelics to treat Addiction

Check out some of the great studies Alaina mentioned in the latest episode of Your Brain on Science! As always, if you need a pdf or access to a paper, please don't hesitate to reach out to us on social media or via the contact button on the website!

Reviews

• Therapeutic effect of psilocybin in addiction: A systematic review

• Classic hallucinogens in the treatment of addictions

• The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens

• The Use of Ibogaine in Treatment of Addiction
  

Clinical/Observational

• Psilocybin-assisted treatment for alcohol dependence: a proof-of-concept study

• Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder

• Assessment of Alcohol and Tobacco Use Disorders Among Religious Users of Ayahuasca

• Hallucinogen use predicts reduced recidivism among substance-involved offenders under community corrections supervision

• Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction

• Psilocybin-occasioned mystical experiences in the treatment of tobacco addiction

• Long-term follow-up of psilocybin-facilitated smoking cessation

• An online survey of tobacco smoking cessation associated with naturalistic psychedelic use

• Prospective examination of the therapeutic role of psychological flexibility and cognitive reappraisal in the ceremonial use of ayahuasca

• Enhancement of Creative Expression and Entoptic Phenomena as After-Effects of Repeated Ayahuasca Ceremonies

Preclinical

• Effects of the synthetic psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) on ethanol consumption and place conditioning in male mice

• Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse

• Psilocybin sex-dependently reduces alcohol consumption in C57BL/6J mice

• LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice

• 5-HT1A Autoreceptors in the Dorsal Raphe Nucleus Convey Vulnerability to Compulsive Cocaine Seeking

• Effects of 2,5-Dimethoxy-4-Methylamphetamine (DOM) and 2-Piperazin-1-yl-Quinoline (Quipazine) on Fentanyl Versus Food Choice in Rhesus Monkeys

• Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice